Choosing the Right Depression Treatment for You: Spravato vs Ketamine

September 19, 2022 by Steve Suntala

Depression is one of the most common mental disorders in the United States. For those with treatment-resistant depression, performing normal everyday activities can be especially challenging. Spravato Nasal Spray with Esketamine and IV Ketamine Infusions are both offered at New Pathways Clinic and are each highly effective methods of fighting treatment-resistant depression.

So then, how do you know which treatment option is right for you?

Esketamine vs Ketamine

If, after trying antidepressants, a patient is still struggling with depressive symptoms, they may have treatment-resistant depression. If this is the case, traditional antidepressants probably aren’t going to be able to help. This is where Esketamine and Ketamine come in.

There are two different types of Ketamine: R-Ketamine and S-Ketamine. While they are nearly identical molecules, they have slightly different effects on the brain. The type of Ketamine used in IV infusions is racemic, which means that is a mixture of both types of Ketamine. Esketamine, on the other hand, is isolated to only contain S-Ketamine, which makes Spravato unique for Esketamine treatments.

While both have proven effective methods for helping with treatment-resistant depression, intravenous Ketamine infusions may present better outcomes due to a number of factors.

Spravato vs Ketamine IV Infusions

Besides containing two types of Ketamine, Spravato and Ketamine Infusions differ in a number of ways. One of the most prominent differences is the method of delivery.

Ketamine infusions are given through an IV over 40 minutes precisely. This allows the provider exact control over the experience and can enhance the cognitive effects of the treatment. Meanwhile, Spravato is self-administered in two to three intranasal sprays over five-minute increments, and acts as an alternative for patients who would prefer to avoid an IV or needles altogether.

For a more informative comparison between Spravato Nasal Spray and IV Ketamine Infusions, you can check-out our helpful chart here.

New Pathways Clinic in Cleveland

New Pathways Clinic is dedicated to helping patients live the life you deserve. Whether you are suffering from Treatment-Resistant Depression, Post-Traumatic Stress Disorder or Bipolar Disorder, New Pathways is here to help you towards a healthier, happier life with proven ketamine and eskatemine treatments that make a profound difference.

To get started with New Pathways Clinic today, contact us by filling out the form here. For more information on Spravato Treatments, visit our Frequently Asked Questions page. You may also take our easy Ketamine Infusions Quiz to see if this treatment option is the right one for you.

At New Pathways Clinic our heartfelt mission is to establish a holistic mental wellness campus that touches the lives of individuals in the greater Cleveland, Columbus, and Cincinnati regions. We are dedicated to combining state-of-the-art mental health treatments, like Ketamine therapy infusions and Spravato nasal spray, with the expertise of compassionate mental health professionals to treat depression, anxiety, PTSD, migraines, and bipolar disorder.

Our unwavering commitment drives us to continuously evolve and adapt as the scientific landscape of ketamine research expands and diversifies, leading to innovative mental health treatments. We are determined to pave the way for a healthier future for Cleveland, central Ohio, and southern Ohio.

New Pathways Clinic also offers Semaglutide & Tirzepatide weight-loss shots, ketamine-assisted psychotherapy, and  ketamine/Spravato support groups for patients.

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