Ketamine Clinics in Cleveland, OH

Serving patients across Greater Cleveland through our Cleveland (East) (Willoughby) and Cleveland (West) (Middleburg Heights) clinics.

Phone: 440-973-8400
Email: [email protected]

Welcome to New Pathways Clinic in Cleveland

Cleveland (East)
Cleveland (West)

Our practice offers doctor-monitored ketamine treatments in a calm, compassionate setting designed for healing and recovery. If traditional medications or therapy have not provided enough relief, our specialized medical team is here to help you regain clarity, emotional balance, and momentum in your life.

Located in Greater Cleveland, with convenient access for patients across Cuyahoga County, our Cleveland ketamine clinics deliver safe, evidence-based care tailored to your unique mental health journey.

We serve patients with ketamine treatment throughout the greater Cleveland metro area, including Downtown Cleveland, Lakewood, Parma, Lorain, Westlake, Elyria, Cleveland Heights, Euclid, and Strongsville.

What Is Ketamine Therapy?

Ketamine therapy is a fast-acting, science-backed medical treatment designed for individuals in Cleveland navigating persistent mental health challenges. Originally developed as an FDA-approved anesthetic, low-dose intravenous (IV) ketamine is used in psychiatric care to offer a distinct alternative to standard approaches:

  • Rapid Relief: Unlike traditional oral antidepressants that can take weeks or months to build up in your system, IV ketamine works rapidly.
  • Controlled Environment: Care is delivered within a safe, doctor-monitored setting tailored to your needs.
  • Alternative Pathway: It provides targeted support for patients seeking results when traditional medications fall short.


By approaching mental health from a unique biological pathway, Cleveland ketamine therapy gives patients a powerful option for achieving real, timely relief.

Conditions Ketamine Treats at Our Cleveland Clinics

We utilize precise, individualized IV protocols to help patients navigate persistent mental health challenges. Our Cleveland ketamine providers deliver localized, evidence-based care for adults struggling with:

Quieting hypervigilance, nervous system overload, and constant internal noise through specialized ketamine for anxiety protocols.

Providing rapid relief during severe depressive phases when traditional mood stabilizers fall short with targeted ketamine therapy for bipolar disorder.

Helping individuals who have tried multiple oral medications without sufficient relief regain mental flexibility using ketamine for depression.

Interrupting rigid thought loops, intrusive thoughts, and compulsive behaviors through clinical ketamine therapy for OCD.

Assisting patients in processing deeply rooted trauma by creating emotional distance from past triggers with ketamine for PTSD.

How Does Ketamine Therapy Work?

Traditional psychiatric medications primarily adjust neurotransmitters like serotonin or norepinephrine. Ketamine therapy in Ohio operates differently by targeting glutamate—the primary chemical messenger in the brain responsible for learning, memory, and neural communication.

By blocking NMDA receptors, low-dose IV ketamine in Cleveland rapidly stimulates synaptogenesis, which is the creation of new neural connections. This process restores damaged brain pathways, interrupts rigid thought loops, and promotes neuroplasticity. 

Ultimately, this allows your brain to form healthier communication patterns and break free from deeply ingrained emotional distress.

Treatments Offered at Our Cleveland Clinics

While IV ketamine infusions serve as our primary core modality at this facility, New Pathways provides a complete ecosystem of advanced care. Patients in the greater Cleveland area can access multiple evidence-based options under one roof:

Ketamine Treatment in Cleveland, OH

Direct intravenous therapy providing high bioavailability and precise dose monitoring for rapid symptom relief.

Combining low-dose ketamine sessions with structured integration therapy to help process deep emotional insights.

An FDA-approved, insurance-covered esketamine nasal spray specifically indicated for treatment-resistant depression.

A non-invasive therapy that uses targeted magnetic pulses to stimulate underactive brain networks involved in mood and emotional regulation.

What to Expect During Your IV Ketamine Treatment Session

We prioritize your physical safety, emotional security, and personal comfort at every step of the process. Before your session begins, you will rest in a quiet, comfortable private room where our clinical staff will review your vitals and place a small IV line.

During the 40-minute infusion, you will relax in a reclining chair. Many Cleveland patients experience a gentle floating sensation, a shift in perception, or a feeling of distance from their daily stress, all while our medical team continuously monitors your vital signs throughout the entire process.

After the infusion finishes, you will spend roughly 20 to 30 minutes relaxing in your room as the physical effects wear off. Because ketamine in Cleveland temporarily impacts motor skills, you will need a designated driver to take you home.

Hear from Our Ketamine Patients

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Joe Sterne profile picture
Joe Sterne
96 days ago
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Lindsay Hackenberg profile picture
Lindsay Hackenberg
123 days ago
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I’ve always had a great experience here. The nurses are kind and compassionate and cater to your experience.
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Cassi Paul profile picture
Cassi Paul
175 days ago
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The people here are incredibly sweet. They have amazing bedside manner and make sure youre comfortable before and during your appointment. Im on treatment 6 and its saving my life
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Mark A. Yeast profile picture
Mark A. Yeast
229 days ago
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The compassion and kindness shown ro me is above and beyond. Each employee is kind and helpful, making this a pleasant experience for me. I thank you New Pathways for giving me life back, with class. Tony is very professional and kind explaining things to me about the product and program. He is kind to make sure that I am taking the right meds before my treatment. The office staff are top notch and are very helpful with my appointments and making sure I am comfortable. The nurses are the best and I have come to look at them as family. Their care is supreme and I really feel like I matter and I am healing on the inside. Thank you Steve and Destiny for giving me a haven and making my life a full one avain.
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Michelle C profile picture
Michelle C
239 days ago
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The staff at New Pathways are always kind and cheerful and make you feel welcome. The treatment rooms have a relaxing ambiance. I highly recommend going here if you have persistent issues with depression.
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Joe Ebner profile picture
Joe Ebner
333 days ago
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Steve and team are wonderful and care about their work. Would recommend to anyone
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Victoria MacGregor profile picture
Victoria MacGregor
343 days ago
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Everyone is super wonderful. I am completely satisfied with my treatments
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Ashley profile picture
Ashley
383 days ago
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Everyone here is so kind. The treatment has been very effective. After a couple treatments I already felt lighter and better able to function. The treatment rooms are comfy and conducive to healing. The staff are very warm and you can tell they want to help any way they can.
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adam darst profile picture
adam darst
386 days ago
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What an amazing place!! The staff is absolutely top notch, kind and knowledgeable and always willing to answer any questions or help you in any way. The services here have helped me immensely and the staff has made every step of the way comfortable and easy.
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Marybeth Novoselsky profile picture
Marybeth Novoselsky
450 days ago
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Excellent treatment. The staff is very attentive. I do ketamine infusion and it's been wonderful. You have to go here!!!!

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Check Out All Our New Pathways Locations

Cincinnati

We are now providing ketamine therapy at our Cincinnati location in southern Ohio. The clinic is off Route I-275, making it easy for patients throughout the region to reach our services.

Cleveland (East)

Our Willoughby ketamine clinic is located off OH-306 (Chillicothe Road) near the heart of the city, just minutes from downtown and accessible from Route 2 and I-90. 

Cleveland (West)

Residing just off Route 71, our ketamine clinic in Middleburg Heights makes it easily accessible from surrounding areas in the greater Cleveland region.

Columbus

Our team also serves patients with state-of-the-art ketamine treatment for those in the Columbus region. Our Columbus clinic is conveniently located off Route 270 in Dublin.

Toledo

We are now providing ketamine therapy at our Toledo-area location in Maumee. Situated on Holland Road right off I-80/I-90 and US-23, our clinic offers easy access for patients throughout Lucas County.

Taking the Next Step with Our Cleveland Ketamine Clinics

If you have further questions after browsing the content in this section, please do not hesitate to contact our Middleburg Heights or Willoughby locations, and we will get back to you quickly. 

You can also request a free, no-strings-attached phone consultation with one of our staff to learn if ketamine treatments in Cleveland will be a wise treatment option for your particular needs. We’re standing by to have that conversation with you!