What Are Migraines?

Migraines are a chronic and painful neurological condition. There is no agreed upon cause of migraines, both genetics and environment appear to be factors. There is also no definitive treatment to turn to that complete or lasting relief by itself. What we do know about migraines is that their symptoms are debilitating for the people who experience them. Migraine attacks can last hours or even days and often prevent the maintaining an ordinary life.  

What Are the Symptoms of Migraines?

  • Throbbing and Pulsing Pain in the Head (Often on One Side) 
  • Sensitivity to Light and Sound 
  • Nausea and Vomiting 
  • Auras (Visual, Auditory, and Physiological Distortions Prior to the Attack) 
  • Neck Stiffness, Mood Changes, and Constipation (Prior to Attacks) 

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How Can Ketamine Infusions Help with Migraines?

One reason Ketamine infusions are promising for migraines because they can stop an attack immediately. “Pre-treatment pain scores ranged from 9 to 10. All patients achieved a target pain level of 3 or less for 8 hours” (Journal of Headache and Pain). They also show some promise for improving the neurochemistry in the brain to prevent further attacks. 

Ketamine is one the only treatments for migraines that works by increasing glutamate in the brain by interacting with the NDMA receptor. “The simplest and most elegant explanation proposed for ketamine’s chronic pain–relieving properties is that it ‘resets the CNS,’ in essence reversing the deleterious effects of central sensitization by virtue of its NMDA-receptor antagonistic effects” (Journal of Chronic and Interventional Pain) 

While Ketamine is an experimental treatment for migraines that still requires further research, a retrospective study completed by Dr. Andrew Sewell produced promising results: 

  • In 162 patients with Refractory Migraines, 150 reported greater than 50% reduction in their pain. 
  • In 39 patients with Chronic Migraine, 26 reported greater than 50% reduction in their pain. 

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Why Choose New Pathways Clinic for Your Ketamine Infusions for Migraines?

At New Pathways Clinic we are empathetic with patients who struggle with Migraines. We understand that many of them have not found relief with traditional treatments. With 10 years of experience providing ketamine infusions, you can trust our Family Nurse Practitioner Nora Finnegan to provide professional care.   

New Pathways and Nora are experts at providing ketamine treatments, but we are not pain management specialists. With that in mind we require approval or a referral from your primary care provider. We will always work in collaboration with the doctor in charge of your pain management to ensure they are updated of your progress. 

Do you need an option for emergency relief for long lasting migraine attack? Do other treatments provide only fleeting or insignificant relief?

Then ask your primary provider if ketamine infusion could be a part of your treatment plan and reach out to us.


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Our mission at New Pathways Clinic is to create a holistic mental wellness campus for the greater Cleveland region, combining cutting-edge treatments like Ketamine infusions and Spravato with health professionals specialized in providing accompanying therapy and lifestyle education. We strive to grow and adapt as the scientific body of research continues to expand and diversify for innovative mental health treatments that will lead Cleveland into a healthier future.