Case Study: Ketamine Treatment Reverses Amblyopia

August 16, 2022 by Steve Suntala

In recent years, ketamine treatments have been safely administered in low doses as an alternative to traditional antidepressants. Patients can receive these treatments through an IV or in the form of Spravato Nasal Spray—both of which have proven to be effective remedies for depression, anxiety, PTSD and more.


Although ketamine is generally used as an anesthetic, or to treat depression and related maladies, a recent case study shows that subanesthetic ketamine can be used to successfully treat amblyopia, also known as lazy eye.

Mayo Clinic writes that lazy eye (amblyopia) is reduced vision in one eye caused by abnormal visual development early in life. The weaker — or lazy — eye often wanders inwards or outwards.
Amblyopia generally develops from birth up to age 7 years of age, and is the leading cause of decreased vision among children.


Dr. Steve Greico, along with a number of other post-doctoral scholars, studied the effects of subanesthetic ketamine as a treatment for lazy eye in adult mice over the course of several days.

In an interview with, Dr. Greico states, “Our group, the Xiangmin Xu laboratory, at the University of California, Irvine (UCI) has uncovered the mechanism of action by which a single low dose of ketamine induces neural plasticity in the brain, or at least in the visual cortex. The visual cortex has a ‘critical period’ during development, which is a window of time in which neural circuits are highly plastic.  If one eye has poor inputs during this critical period, the brain will ultimately ignore that eye, resulting in permanent non-reversible vision loss, a condition known as amblyopia or ’lazy eye’.”

Dr. Greico goes on to say, “To our amazement, experimental animals which were made to have a lazy eye, recovered vision in that eye even as adults if given a ketamine treatment. This unequivocally proves the potential of ketamine to induce significant levels of neural plasticity.”

For more reporting on this exciting discovery, please click here for detailed info from the UCI School of Medicine.

Ketamine Treatments at New Pathways Clinic

Ketamine is taking the world by storm. Whether you are living with depression, anxiety, bipolar disorder or some other condition, ketamine treatments may be your solution. If you or someone you know is suffering from a treatment-resistant condition, New Pathways Clinic in Cleveland is here to help. Contact us to schedule an appointment and experience the life-changing benefits of ketamine treatments today.

While you’re here, feel free to read FAQs and answers about ketamine treatments to gain more understanding on this remarkable treatment option. You can also schedule a free, no-strings-attached consultation to learn if ketamine or Spravato is right for you.

At New Pathways Clinic our heartfelt mission is to establish a holistic mental wellness campus that touches the lives of individuals in the greater Cleveland, Columbus, and Cincinnati regions. We are dedicated to combining state-of-the-art mental health treatments, like Ketamine therapy infusions and Spravato nasal spray, with the expertise of compassionate mental health professionals to treat depression, anxiety, PTSD, migraines, and bipolar disorder.

Our unwavering commitment drives us to continuously evolve and adapt as the scientific landscape of ketamine research expands and diversifies, leading to innovative mental health treatments. We are determined to pave the way for a healthier future for Cleveland, central Ohio, and southern Ohio.

New Pathways Clinic also offers Semaglutide & Tirzepatide weight-loss shots, ketamine-assisted psychotherapy, and  ketamine/Spravato support groups for patients.

Keep In Touch

Stay informed on ketamine treatments, Spravato, and mental-health wellness at New Pathways Clinic in Cleveland via our free newsletter.

© New Pathways 2024