Phone: (419) 482-1168
Email: [email protected]
Our practice offers doctor-monitored IV ketamine therapy in a calm, compassionate setting designed to improve your mental health. If traditional medications or therapy have not provided enough relief, our specialized medical team is here to help you regain clarity, emotional balance, and momentum in your life.
Located in Maumee, Ohio, with convenient access for patients across Toledo, Sylvania, Perrysburg, and surrounding Lucas County communities, our Toledo ketamine clinic delivers safe, evidence-based care tailored to your unique mental health journey.
Ketamine therapy is a fast-acting, science-backed medical treatment designed for individuals navigating persistent mental health challenges. Originally developed as an FDA-approved anesthetic, New Pathways Clinic’s low-dose intravenous (IV) ketamine is used in psychiatric care to offer a distinct alternative to standard approaches:
By approaching mental health from a unique biological pathway, Toledo ketamine therapy gives patients a powerful option for achieving real, timely relief.
We utilize precise, individualized IV protocols to help patients navigate persistent mental health challenges. Our Toledo ketamine providers deliver localized, evidence-based care for adults struggling with:
Quieting hypervigilance, nervous system overload, and constant internal noise through specialized ketamine for anxiety protocols.
Providing rapid relief during severe depressive phases when traditional mood stabilizers fall short with targeted ketamine therapy for bipolar disorder.
Helping individuals who have tried multiple oral medications without sufficient relief regain mental flexibility using ketamine for depression.
Interrupting rigid thought loops, intrusive thoughts, and compulsive behaviors through clinical ketamine therapy for OCD.
Assisting patients in processing deeply rooted trauma by creating emotional distance from past triggers with ketamine for PTSD.
Traditional psychiatric medications primarily adjust neurotransmitters like serotonin or norepinephrine. Ketamine therapy in Ohio operates differently by targeting glutamate—the primary chemical messenger in the brain responsible for learning, memory, and neural communication.
By blocking NMDA receptors, low-dose IV ketamine in Toledo rapidly stimulates synaptogenesis, which is the creation of new neural connections. This process restores damaged brain pathways, interrupts rigid thought loops, and promotes neuroplasticity.
Ultimately, this allows your brain to form healthier communication patterns and break free from deeply ingrained emotional distress.
While IV ketamine infusions serve as our primary core modality at this facility, New Pathways provides a complete ecosystem of advanced care. Patients in the greater Toledo area can access multiple evidence-based options under one roof:
Direct intravenous therapy providing high bioavailability and precise dose monitoring for rapid symptom relief.
Combining low-dose ketamine sessions with structured integration therapy to help process deep emotional insights.
An FDA-approved, insurance-covered esketamine nasal spray specifically indicated for treatment-resistant depression.
We prioritize your physical safety, emotional security, and personal comfort at every step of the process. Before your session begins, you will rest in a quiet, comfortable private room where our clinical staff will review your vitals and place a small IV line.
During the 40-minute infusion, you will relax in a reclining chair. Many patients experience a gentle floating sensation, a shift in perception, or a feeling of distance from their daily stress, all while our medical team continuously monitors your vital signs throughout the entire process.
After the infusion finishes, you will spend roughly 20 to 30 minutes relaxing in your room as the physical effects wear off. Because ketamine in Toledo temporarily impacts motor skills, you will need a designated driver to take you home.
Matthew Eifrid is a dual-certified Psychiatric Mental Health and Family Nurse Practitioner and
Clinical Director of New Pathways Clinic Toledo. With more than 30 years of experience in primary care and psychiatry, he provides individualized care for a range of mental health conditions, with a particular interest in treatment-resistant depression and ketamine and esketamine therapies. Matt is committed to a welcoming clinic and close collaboration with patients’ other providers.
1. SCHEDULE
AN EVALUATION
2. FILL OUT
OUR ONLINE FORM
3. EVALUATION
WITH OUR PROVIDER
4. MAKE
APPOINTMENTS
5. RECEIVE
TREATMENTS
6. MAINTAIN
TREATMENT PLAN
What sets our Toledo clinic apart most is the individualized, one-on-one care. Patients tell us all the time that the way we focus on one person at a time feels different from what they’ve experienced elsewhere — many clinics and hospitals treat people in large, open rooms with only a curtain between patients. Here, every treatment happens in a private room designed for psychiatric care.
Our Toledo ketamine practice also treats psychiatric conditions specifically — we’re not a general infusion center that added ketamine to a broader list of services. We offer IV ketamine, Spravato, and ketamine-assisted psychotherapy, track symptoms throughout care, and build maintenance plans around each patient’s response.
Just as much of it comes down to the team. Our Toledo ketamine nurses, nurse practitioners, and administrative staff are dedicated and compassionate, and they go the extra mile to make sure each patient is heard and has what they need to be comfortable and successful in treatment.
Dr. Ryan O’Neill, our Medical Director, oversees your care. He trained in emergency medicine at Ohio State and has years of hands-on experience with ketamine, and he sets the standards every treatment plan follows.
The person who sits down with you in Toledo for your evaluation and manages your medication is a psychiatric nurse practitioner — someone who has worked with people in crisis, in intensive care, in addiction recovery, and with depression that hasn’t responded to other treatments. They’ve seen a lot, and very little surprises them.
During your Toledo ketamine infusion, a registered nurse stays with you. They’re trained in our ketamine protocols and know how to help if you feel anxious or nauseated, or if your blood pressure shifts. You’re never left alone to wonder whether something is normal.
And our licensed KAP therapist is here for the work that happens between appointments, when you’re making sense of what treatment is opening up.
We don’t use a single protocol for every ketamine diagnosis in Toledo. We review your symptom pattern, prior medication trials, therapy history, medical conditions, and goals before building a plan.
Treatment-resistant depression often starts with six IV infusions over two to three weeks; PTSD calls for more emphasis on pacing and emotional safety; OCD treatment uses ketamine as an adjunct to established care. Diagnosis informs the plan but doesn’t determine it by itself.
We prefer to work alongside the professionals who already know you. Toledo ketamine treatment is meant to strengthen your existing mental health plan, not replace it.
With your authorization, we can review records, coordinate medication questions, and share progress — and we encourage therapy during the period of increased psychological flexibility that can follow treatment. If you don’t have a psychiatrist, our nurse practitioners can evaluate and prescribe when appropriate.
The decision depends on diagnosis, treatment history, medical appropriateness, insurance coverage, and route preference.
IV ketamine in Toledo allows precise dose adjustment based on weight, response, and tolerability. Spravato is an FDA-approved intranasal option with specific eligibility requirements, often a good fit for someone who prefers to avoid an IV or has coverage that makes it accessible. KAP combines ketamine with preparation and integration therapy, and helps most when trauma or grief is central to symptoms.
Plan to arrive 15 minutes early to finish your paperwork. Your nurse will bring you back to your own private treatment room, where you’ll give a urine sample for routine screening and see your nurse practitioner for a brief check-in. Your Toledo ketamine nurse then walks you through what to expect and makes sure you’re comfortable before starting.
You’ll have a small IV placed in one arm and gentle monitors on the other, tracking your blood pressure, heart rate, and oxygen throughout. A nurse stays with you the whole time.
The infusion itself runs about an hour — roughly 40 minutes of ketamine, then a 20-minute saline flush. Most people describe a floaty, dreamlike feeling and may see colors and patterns; it’s expected, and it fades as the medicine wears off. Calming music and an eye mask make it more relaxing, and we provide both.
By the end of your ketamine session in Toledo, you’ll likely feel tired but clear-headed. Your nurse will check that you’re ready before discharging you to your ride home. Plan on about two hours from check-in to discharge, so nothing feels rushed.
Maintenance is based on your response, not a fixed schedule. We review symptom scores, functional improvement, and how long the benefit lasts.
When possible, our Toledo clinic schedules a ketamine booster as symptoms begin to reappear rather than waiting for a full relapse. Intervals range from about once a month to once or twice a year.
Spravato follows its own structure, moving from twice-weekly induction to weekly or every other week.
Yes — a private room, not an open infusion bay. Toledo ketamine staff enters to monitor you, but you won’t be treated alongside other patients.
Lighting can be dimmed, and you can bring your own music or use one of our playlists. Blankets and pillows are available, and staff will make reasonable temperature adjustments.
Wear comfortable clothing, and tell our Toledo ketamine therapists about any sensory sensitivities before treatment begins.
You won’t be able to drive yourself home after ketamine treatment in Toledo, and we know that isn’t always simple to arrange — so we work with you on it. Many patients have a friend or family member drive them, and that person is welcome to wait in the lobby or in the room with you, or drop you off and come back at the end.
If you don’t have someone available, we can order a rideshare to get you back home; you’d be responsible for the cost of the ride. We go over your transportation with you before ketamine therapy begins, so if it’s a concern, tell us early, and we’ll help you find something that works.
Cincinnati
We are now providing ketamine therapy at our Cincinnati location in southern Ohio. The clinic is off Route I-275, making it easy for patients throughout the region to reach our services.
Cleveland (East)
Our Willoughby ketamine clinic is located off OH-306 (Chillicothe Road) near the heart of the city, just minutes from downtown and accessible from Route 2 and I-90.
Cleveland (West)
Residing just off Route 71, our ketamine clinic in Middleburg Heights makes it easily accessible from surrounding areas in the greater Cleveland region.
Columbus
Our team also serves patients with state-of-the-art ketamine treatment for those in the Columbus region. Our Columbus clinic is conveniently located off Route 270 in Dublin.
Toledo
We are now providing ketamine therapy at our Toledo-area location in Maumee. Situated on Holland Road right off I-80/I-90 and US-23, our clinic offers easy access for patients throughout Lucas County.
We look forward to serving our Toledo neighbors with our innovative ketamine therapy. Please reach out with any questions to our clinic!
Taking the next step toward relief shouldn’t feel overwhelming. Contact our team today to schedule an initial consultation, discuss pricing and insurance options, and learn whether ketamine treatment in Toledo is the right choice for your path forward.
